Erectile Dysfunction — The Canary In The Mineshaft?
Comments: 0 - Date: May 25th, 2007 - Categories: Uncategorized
New research into urologic conditions - such as erectile dysfunction - indicate that these disorders could be associated with or precursors to more serious conditions, and suggest a need for practitioners to view these diseases in the greater context of total health as opposed to isolated disorders. A special session highlighting the association on urologic diseases with non-urologic conditions such as heart disease and metabolic syndrome was presented during the 102nd Annual Scientific Meeting of the American Urological Association. A special session for the media was moderated by Marshall L. Stoller, M.D.
ENDOTHELIAL DYSFUNCTION AND OXIDATIVE STRESS ASSOCIATED WITH THE METABOLIC SYNDROME CAN BE REVERSED BY A CHRONIC TREATMENT WITH SILDENAFIL (Abstract 686)
Metabolic syndrome is characterized by a number of conditions, including elevated blood pressure, excess body fat around the waist and insulin resistance. Many patients with these conditions also exhibit endothelial dysfunction with increases in oxidative stress and decreases in nitric oxide production - which has been related to erectile dysfunction (ED). Researchers from France explored whether treatment with sildenafil citrate - a common pharmacologic treatment for Erectile Dysfunction - could improve endothelial dysfunction in a rat model.
Researchers administered sildenafil to fructose-fed rats to achieve plasma concentrations known to give efficacy in men and observed endothelial function and oxidative stress in the animals during treatment and one-week after treatment had been stopped. It was observed that chronic sildenafil treatment improved endothelial function and oxidative stress, suggesting that this treatment could be a benefit for cardiovascular indications as well as erectile dysfunction.
ERECTILE DYSFUNCTION AND CORONARY HEART DISEASE (Abstract 864)
Research has shown a connection between erectile dysfunction (ED) and cardiovascular disease (CVD) in men, and has established a need to consider one a precursor to the other. Researchers further evaluated the association of these two conditions and whether the association could be age-related.
A random sample of men from the Olmsted County population was evaluated by questionnaire, and community medical records of the subjects were examined. Logistical regression models examined the associations between ED and CVD. Men with CVD were 4.2 times more likely to have ED than men without heart disease. The results underscore a need to consider sexual function in men with heart disease and CVD in men with ED.
Source: Medicalnewstoday
ENDOTHELIAL DYSFUNCTION AND OXIDATIVE STRESS ASSOCIATED WITH THE METABOLIC SYNDROME CAN BE REVERSED BY A CHRONIC TREATMENT WITH SILDENAFIL (Abstract 686)
Metabolic syndrome is characterized by a number of conditions, including elevated blood pressure, excess body fat around the waist and insulin resistance. Many patients with these conditions also exhibit endothelial dysfunction with increases in oxidative stress and decreases in nitric oxide production - which has been related to erectile dysfunction (ED). Researchers from France explored whether treatment with sildenafil citrate - a common pharmacologic treatment for Erectile Dysfunction - could improve endothelial dysfunction in a rat model.
Researchers administered sildenafil to fructose-fed rats to achieve plasma concentrations known to give efficacy in men and observed endothelial function and oxidative stress in the animals during treatment and one-week after treatment had been stopped. It was observed that chronic sildenafil treatment improved endothelial function and oxidative stress, suggesting that this treatment could be a benefit for cardiovascular indications as well as erectile dysfunction.
ERECTILE DYSFUNCTION AND CORONARY HEART DISEASE (Abstract 864)
Research has shown a connection between erectile dysfunction (ED) and cardiovascular disease (CVD) in men, and has established a need to consider one a precursor to the other. Researchers further evaluated the association of these two conditions and whether the association could be age-related.
A random sample of men from the Olmsted County population was evaluated by questionnaire, and community medical records of the subjects were examined. Logistical regression models examined the associations between ED and CVD. Men with CVD were 4.2 times more likely to have ED than men without heart disease. The results underscore a need to consider sexual function in men with heart disease and CVD in men with ED.
Source: Medicalnewstoday